The Aging Brain Cohort (ABC) Study

The Aging Brain Cohort (ABC) study’s mission is to discover how brain health is related to the problems that coincide with aging. With your help, we hope to identify risk factors for a host of age-related problems (e.g. cognitive decline, Alzheimer’s disease, stroke, etc.).

NOW RECRUITING 20-80 year old adults

The latest updates in our Spring Newsletter features  preliminary results from our COVID-19 study on brain health as well as interesting features of on-going opportunities.  

About ABC

The Aging Brain Cohort Study (ABC) is a large-scale study being run by Dr. Julius Fridriksson at the University of South Carolina that examines how people’s brain health changes as they get older. Our goal is to find out why some brains are more resistant to age related decline than others.

In order to answer this question, we are going to gather information from 800 residents of South Carolina. We will gather data on diet, sleep, exercise, gender, income, race, education, and language. We will also conduct a series of tests including an MRI, EEG, and sample blood and cell tests.

Click on the video link to meet the team and get a behind-the-scenes look at the state of the art testing you’ll experience if you choose to participate.

Using this data, we will examine the relationship between these measures and brain health across the lifespan (ages 20-80). All of this information will be stored in the ABC Biobank which will serve as an invaluable resource for researchers trying to identify risk factors for age-related brain decline.

As of July 2023, we have reached 400 participants and are halfway to our goal of “800”!

What to Expect

If  you decide to participate in the ABC study, you will spend two days with our team of psychologists and neuroscientists. During the first day we will assess your cognitive and motor abilities, and we will record signals generated by your brain as you perform simple language tasks.

During the second day, we will collect a blood sample (for DNA analysis) and capture pictures of your brain using magnetic resonance imaging (MRI). You will be compensated for your participation (up to $150 in VISA prepaid gift cards).


While participants will not benefit directly from being in this study, they will be compensated for time spent with our staff. Data from the ABC study will help researchers understand the relationship between various biologic measures (e.g. MRI, EEG and DNA) and age-related cognitive decline and stroke.


If you are age 20-80 and can understand spoken and written English you may be able to participate. Check your eligibility by clicking the link below and answering a few questions. If you qualify for participation, our friendly study staff will contact you by phone to tell you more about the study.

Get In Touch

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